Genocide (man, I loathe your handle!

)
How many friends are traveling together?
If you're on a budget, there are many less expensive places to stay closer to the action that are chica friendly. Search the "Hotels" section on this site. Some others to consider:
The Hotel Gran Via, right on Avenida Central, about three blocks west of the Presidente and only four blocks from the Blue Marlin
Hotel Castillo: Chica friendly, near Sportsmen's Lodge, New Fantasy Massage and not far from many other mongering places.
Hotel Del Rey has been spurned by many veterans on this Forum, but you gotta admit, it's right in the belly of the beast and may be a good place to stay during your first visit.
The Hotel Presidente is decidedly monger-friendly, although you'll be limited to one chica at a time per room.
Hotel Europa (NOT the Radisson Europa; the Hotel Europa on calle Central is the one I'm talking about). Chica-friendly if you're not an as*hole.
Do your homework, and as the always-brilliant Prolijo wrote above, you've got time to make alternate hotel reservations. All the hotels I've listed are secure, clean, friendly and offer good service (although some people have complained about the late-night noise level at the Gran Via and Presidente, and at the Del Rey if your room is directly above the casino).
Hope this helps. Again, search this site for hotel reviews.
Now, for the real budget monger: Hotel Johnson, Hotel Asia, Gran Hotel Centroamericano, Royal Dutch... the list goes on and on.
